Final answer:
When a patient's beta cells do not function properly and insulin levels are low, it results in both increased urine production and higher than normal blood glucose levels.
Step-by-step explanation:
The correct answer is E. Both B and C. When a patient's beta cells are not functioning properly and their insulin levels are low, it indicates a problem with insulin production. This means that the insulin receptors are not being upregulated, as stated in option A. Instead, the low insulin levels lead to increased urine production, as the excess glucose in the blood is not being properly absorbed and is excreted in the urine. Additionally, the low insulin levels result in a higher than normal blood glucose level, as insulin is responsible for regulating glucose levels in the blood.