Question

Excessive bleeding caused by congenital lack of factor VIII or IX:

A) Autoimmune thrombocytopenic purpura
B) Erythremia
C) Granulocytosis
D) Polycythemia vera
E) Hemophilia

Answer 1

Excessive bleeding due to the lack of factor VIII or IX is known as hemophilia, a genetic disorder caused by an inadequate production of clotting factors. The condition is typically X-linked and treated with infusions of clotting factors.

Step-by-step explanation:

Hemophilia: The Clotting Disorder

Excessive bleeding due to a congenital lack of factor VIII or IX corresponds to the genetic disorder known as hemophilia. Hemophilia A involves an inadequate production of clotting factors, specifically factor VIII, and accounts for about 80% of hemophilia cases. Hemophilia B, also caused by an inadequate production of clotting factors, is due to a deficiency in factor IX and makes up about 20% of cases.

Both Hemophilia A and B are X-linked disorders, often passed from a carrier mother to her male offspring. Hemophilia C, which is much rarer, involves a deficiency in factor XI and can be observed in individuals with just one copy of the gene.

The correct answer to the excessive bleeding problem due to a lack of factor VIII or IX is E) Hemophilia. Regular treatment for this condition includes infusions of clotting factors from healthy donors, and future treatments may involve genetic therapy.