Final answer:
Yes, Addison's disease affects the adrenal medulla. While primarily affecting the adrenal cortex, it can also lead to hyposecretion of mineralocorticoids
Step-by-step explanation:
Yes, Addison's disease does affect the adrenal medulla. Addison's disease, also known as primary adrenal insufficiency, is characterized by the reduced production of cortisol from the adrenal gland. The adrenal medulla, which is part of the adrenal gland, releases hormones in response to acute, short-term stress mediated by the sympathetic nervous system (SNS). While Addison's disease primarily affects the adrenal cortex, it can also lead to hyposecretion of mineralocorticoids, which are produced in the adrenal medulla.