Final answer:
Weight loss and lethargy may indicate a hypersecretion of thyroid hormones.
Step-by-step explanation:
Hyperthyroidism is a condition in which the thyroid gland is overactive, leading to an excess secretion of thyroid hormones. The symptoms of hyperthyroidism include weight loss, increased heart rate, and increased body heat production. Therefore, option A and option D may indicate a hypersecretion of thyroid hormones.