Final answer:
Endotracheal drug administration is the least desirable route for pediatric resuscitation when IV access is not available, and higher dosages may be needed. For home administration of antimicrobials for systemic infections, the oral route is convenient unless the condition requires higher plasma levels of the drug, where intravenous administration is preferred.
Step-by-step explanation:
The correct statement about endotracheal drug administration during resuscitative efforts for pediatric patients is that it is the least desirable route of administration. When intravenous (IV) access is not available, drugs may be given via the endotracheal tube, but this is considered less ideal. In such situations, the dosage administered endotracheally may need to be higher than the IV drug dose to ensure adequate plasma levels are achieved.
Regarding the choice of route for administering antimicrobials to treat a systemic infection at home, the oral route is generally appropriate and convenient. However, when a drug is not absorbed in the gastrointestinal (GI) tract or when higher plasma levels are necessary, the parenteral route (such as intravenous) is preferred, usually performed in healthcare settings. The exact choice of route will depend on the specific drug properties, the infection being treated, and patient factors such as accessibility to healthcare facilities or need for rapid therapeutic levels.