Final answer:
During CPR, intra-arterial pressures must be maintained within a range that ensures effective circulation, typically aiming for a Mean Arterial Pressure (MAP) of at least 60 mm Hg to avoid ischemia and hypoxia.
Step-by-step explanation:
Intra-arterial pressures during CPR should be maintained within a certain range to be effective. An important measure of sufficient blood circulation during CPR is the Mean Arterial Pressure (MAP), which normally falls within 70-110 mm Hg. During CPR, it's crucial to achieve and maintain a MAP that can ensure circulation to and through the tissues, preventing conditions such as ischemia and hypoxia.
Figures indicate that maintaining a MAP of at least 60 mm Hg is necessary for adequate blood flow, and anything lower for an extended time could result in insufficient blood flow (ischemia) and inadequate oxygenation of tissues (hypoxia). Therefore, effective CPR must aim to keep intra-arterial pressures high enough to sustain life, especially considering that neurons are highly sensitive to hypoxia.
Furthermore, pulse pressure, which should be at least 25 percent of systolic pressure, can indicate the effectiveness of the blood being ejected during compressions. A low pulse pressure might signal a low stroke volume, which is inadequate during CPR. Hence, maintaining a sufficient intra-arterial pressure and pulse pressure during CPR is vital for achieving tissue perfusion and oxygenation.