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Which of the following drug is not an amide?

a. procaine
b. lidocaine
c. mepivacaine
d. carbocaine

1 Answer

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Final answer:

Procaine (Novocain) is not an amide, but an ester, while lidocaine, mepivacaine, and carbocaine are amides. The solution of Novocain would be basic due to the ionization of procaine, with ion concentrations and pH calculable via the provided ionization constant.

Step-by-step explanation:

The question pertains to the classification of certain drugs as amides. An amide is a type of functional group found in organic chemistry compounds, characterized by a carbonyl group (C=O) attached to a nitrogen atom (N).

Procaine, also known as Novocain, is not an amide; it's an ester. In contrast, lidocaine, mepivacaine, and carbocaine are all amides. The structure of an ester includes a carbonyl group bonded to an oxygen atom that is further bonded to another carbon atom, rather than the nitrogen found in amides.

Regarding the properties of a solution of Novocain, because procaine is the base form and it will accept a proton (H+) from water to form the conjugate acid, the solution of Novocain will be basic. We can calculate the ion concentrations and pH of the solution using the given ionization constant for procaine.

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