Question

Which of the following conditions can affect the speed of drug biotransformation?

a. cirrhosis
b. hypotension
c. congestive heart failure
d. all of the above

Answer 1

Cirrhosis, hypotension, and congestive heart failure can all affect the speed of drug biotransformation.

Step-by-step explanation:

The speed of drug biotransformation can be affected by all of the above conditions.

1. Cirrhosis: Chronic liver failure can lead to cirrhosis, which can impair the liver's ability to metabolize drugs effectively.
2. Hypotension: Low blood pressure can decrease the blood flow to the liver, affecting drug metabolism.
3. Congestive heart failure: In congestive heart failure, the heart may not pump blood efficiently, resulting in reduced blood flow to the liver, affecting drug metabolism.