Final answer:
Anemia associated with kidney disease is primarily due to inadequate synthesis of erythropoietin (EPO), which is crucial for the production of red blood cells. Kidney disease leads to a decline in EPO production, resulting in a decreased RBC count and compromised oxygen delivery to the body's tissues. The correct option is C.
Step-by-step explanation:
The primary mechanism for the anemia associated with kidney disease is c. Inadequate synthesis of erythropoietin (EPO). Chronic kidney diseases often lead to a decrease in the production of EPO, a critical hormone responsible for the stimulation of red blood cell (RBC) formation in the bone marrow. The kidney is the main organ that produces EPO, accounting for about 85% of the circulating levels, and when its function is impaired due to disease, this can result in anemia.
Anemia that arises due to kidney disease can significantly impact the body's ability to deliver oxygen to the tissues, because of the reduced number of RBCs being produced. This condition is especially concerning in renal failure, where EPO production plummets, leading to difficulty in meeting the body's oxygen demands. Conditions like hemolysis, hemorrhage, or inadequate synthesis of interleukins can also cause anemia, but they do not primarily relate to the anemia seen in kidney disease.