Final answer:
The HIPAA Omnibus Rule of 2013 made business associates of covered entities directly liable for compliance with HIPAA, enhanced penalties for noncompliance, and introduced new breach notification rules.
Step-by-step explanation:
One significant change made to HIPAA by the Omnibus Rule of 2013 is the expansion of privacy and security protection to business associates of covered entities. Business associates, including subcontractors, are now directly liable for compliance with certain privacy and security provisions of HIPAA. This rule strengthens the enforcement of HIPAA by enhancing penalties for noncompliance and introducing new provisions for breach notifications.