Final answer:
The necessary and proper clause has actually been interpreted by the courts to expand the power of the national government, rather than limiting it. Therefore, the given statement is false.
Step-by-step explanation:
The statement in question, 'The necessary and proper clause has had the effect of limiting the power of the national government,' is False. The necessary and proper clause, also known as the elastic clause, is found in Article I, Section 8, Clause 18 of the United States Constitution. It grants Congress the power to make all laws necessary and proper for carrying out its enumerated powers. This clause has actually been interpreted by the courts to expand the power of the national government, rather than limiting it.