Final answer:
The statement about NADH not being able to cross the inner mitochondrial membrane and requiring shuttle systems to transport its electrons is true. Components such as CoQ and cytochrome c are mobile electron carriers that help shuttle electrons within the inner mitochondrial membrane.
Step-by-step explanation:
The statement that NADH cannot cross the inner mitochondrial membrane and that electrons and protons must be carried across by shuttle systems is true. Shuttle systems like the Glycerophosphate shuttle and Malate-Aspartate shuttle facilitate the transport of NADH's electrons into the mitochondria since NADH itself cannot cross the membrane.
The electron transport chain includes several components such as CoQ (ubiquinone) and cytochrome c, which are mobile electron carriers, whereas enzymes like NADH dehydrogenase are bound to the inner mitochondrial membrane and are not mobile. This chain functions to pass electrons from NADH and FADH2 to molecular oxygen, pumping protons from the mitochondrial matrix to the intermembrane space in the process.