Final answer:
The interface between the physical media and the software running on a computer is called the operating system.
Step-by-step explanation:
The interface between the physical media and the software running on a computer is called the operating system. The operating system acts as a mediator between the hardware components of the computer and the software programs that run on it. It provides a set of functions and services that enable software to interact with the computer's hardware, such as managing memory, handling input and output devices, and scheduling tasks.
For example, when you type on a keyboard, the operating system processes the input and passes it to the software program you are using. Similarly, when a program needs to save a file to the hard drive, the operating system takes care of writing the data to the appropriate location on the disk.