Question

The nurse is speaking to a group of genetic students touring the hospital's laboratory. The nurse talks about the possibility of a genetic predisposition for the leukemias being suggested because of the increased incidence of the disease among a number of congenital disorders. Which congenital disorders are these? (Select all that apply.)

a) Down syndrome
b) Prader-Willi syndrome
c) Cushing syndrome
d) Neurofibromatosis
e) Fanconi anemia

Answer 1

Down syndrome, neurofibromatosis, and Fanconi anemia are congenital disorders associated with an increased incidence of leukemia.

Step-by-step explanation:

The congenital disorders that have been associated with an increased incidence of leukemia are:

• Down syndrome: It is a genetic disorder caused by the presence of an extra copy of chromosome 21 in the cells. People with Down syndrome have a higher risk of developing leukemia compared to the general population.
• Neurofibromatosis: It is a genetic condition that causes tumors to form on nerve tissue. People with neurofibromatosis have an increased risk of developing certain types of leukemia.
• Fanconi anemia: It is a rare genetic disorder that affects the bone marrow and leads to a higher risk of developing leukemia.

It is important to note that while the presence of these congenital disorders may increase the risk of leukemia, not all individuals with these disorders will develop leukemia.