Final answer:
Endospores can be destroyed by high temperature and pressure, which can be achieved in an autoclave.
Step-by-step explanation:
Endospores are resistant structures produced by certain bacteria to survive harsh conditions. To destroy endospores, high temperature and pressure are necessary, which can be achieved in an autoclave. Autoclaves raise the temperature above the boiling point of water, effectively killing endospores and other microorganisms.