Question

Outline the receptor-mediated process involving LDL receptors.

a) LDL binding, endocytosis, lysosomal degradation
b) HDL binding, exocytosis, Golgi processing
c) VLDL binding, phagocytosis, mitochondrial uptake
d) Chylomicron binding, autophagy, nuclear transport

Answer 1

Receptor-mediated endocytosis is a process involving LDL receptors. LDL complexes bind to LDL receptors, forming coated pits that invaginate and pinch off to form coated vesicles.

Step-by-step explanation:

Receptor-mediated endocytosis is a process that involves the uptake of cholesterol bound to low density lipoprotein (LDL). First, LDL complexes bind to LDL receptors on the surface of the cell. Then, the receptors and LDL form coated pits, which invaginate and pinch off to form coated vesicles. These vesicles deliver their contents to their cellular destinations and the vesicle membranes are recycled to the plasma membrane.