Final answer:
The statement is false; cells specializing in lipid synthesis have more smooth ER than rough ER, as smooth ER is responsible for lipid biosynthesis, among other functions.
Step-by-step explanation:
The statement that cells carrying out extensive lipid synthesis have more rough ER compared to smooth ER is false. The smooth endoplasmic reticulum (SER) is specifically responsible for lipid biosynthesis among its other functions such as carbohydrate metabolism, detoxification, and calcium ion storage.
In contrast, the rough endoplasmic reticulum (RER) is characterized by the presence of ribosomes on its surface and is significantly involved in the synthesis and modification of proteins.