Final answer:
During meiosis, if a chromosome undergoes loss or rearrangement of genes, it is referred to as a deletion. Deletions can result in a large section of a chromosome being lost, affecting multiple genes and potentially leading to genetic imbalances and lethality in diploid organisms.
Step-by-step explanation:
A chromosome that has missing genes due to loss or rearrangement during the recombination step of meiosis is said to have a deletion. Deletions result in a large section of a chromosome being lost and can involve several to hundreds of genes. This can lead to genetic imbalance and can be lethal to a diploid organism.