Question

Which of the following is caused by an enzyme deficiency, causes abnormal lipid metabolism in the brain, and affects people of the Ashkenazi Jewish population:

a) Sickle cell anemia
b) Tay-Sachs disease
c) Cystic fibrosis
d) Hemophilia

Answer 1

b) Tay-Sachs disease. Tay-Sachs disease is a genetic disorder caused by a deficiency of the enzyme hexosaminidase A. This deficiency leads to the abnormal accumulation of gangliosides in the brain, resulting in progressive neurological deterioration.

Step-by-step explanation:

The correct answer is Tay-Sachs disease.

Tay-Sachs disease is a genetic disorder caused by a deficiency of the enzyme hexosaminidase A. This deficiency leads to the abnormal accumulation of lipid molecules called gangliosides in the brain, which affects the nervous system and leads to progressive neurological deterioration. Tay-Sachs disease is most commonly found in the Ashkenazi Jewish population, although it can affect people of other ethnic backgrounds as well.