Final answer:
The coarse focus knob is used for major adjustments in focus, while the fine focus knob is used for fine-tuning the focus on a bright field microscope.
Step-by-step explanation:
How do the coarse and fine focus knobs work on a bright field microscope?
When using a bright field microscope, the coarse focus knob is responsible for major adjustments in focus, while the fine focus knob is used for fine-tuning the focus. The coarse focus knob is used for large-scale movements when using low and medium power objective lenses (such as 4x and 10x), while the fine focus knob is used for small-scale movements, especially when using high power objective lenses (such as 40x or 100x).