Final answer:
The rapid weight loss during the first week of a diet is due to fluid loss, with the greatest contribution coming from intravascular fluid (blood plasma).
Step-by-step explanation:
The component of the extracellular fluid that contributes the greatest proportion to the rapid weight loss during the first week of a diet is Intravascular fluid, also known as blood plasma.
Extracellular fluid accounts for about 20% of the body weight, with 15% in interstitial fluid and 5% in blood plasma.
During the first week of a diet, as the body adjusts to reduced calorie intake, it uses up stored glycogen, which is stored with water. This leads to fluid loss and a decrease in weight. However, it's important to note that this initial weight loss is mostly water weight and not fat loss.