Final answer:
The release of human growth hormone (hGH) is regulated by growth hormone-releasing hormone (GHRH) and growth hormone-inhibiting hormone (GHIH), with GHRH stimulating and GHIH inhibiting its release.
Step-by-step explanation:
The two hypothalamic hormones that control the release of human growth hormone (hGH) are the growth hormone-releasing hormone (GHRH) and the growth hormone-inhibiting hormone (GHIH), also known as somatostatin. The release of hGH is regulated through hormonal stimuli, where GHRH stimulates its release, and GHIH inhibits it.
This process includes the hormone receptors on cells in the anterior pituitary gland that respond to these hypothalamic hormones. The indirect mechanism of GH action involves insulin-like growth factors (IGFs), which are essential for growth and development, particularly after a meal when nutrient levels are elevated in the blood.