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How does translation work? (6 main steps)

User Elease
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Final answer:

Translation is the process by which mRNA is converted into protein. It involves steps like activation of amino acids, initiation, elongation, termination, post-translational modifications, and protein folding and targeting.

Step-by-step explanation:

Translation is the process by which the genetic information present in a mRNA molecule is converted into protein with specific amino acid sequence. It involves six main steps:

  1. Activation of amino acids: Amino acids are activated by attaching them to transfer RNA (tRNA) molecules.
  2. Initiation: The ribosome binds to the mRNA and the process starts at the start codon (AUG).
  3. Elongation: Amino acids are added one by one to the growing polypeptide chain, with each amino acid being brought in by a specific tRNA molecule.
  4. Termination: The process stops when a stop codon is reached on the mRNA, releasing the completed protein.
  5. Post-translational modifications: The newly synthesized protein may undergo modifications, such as folding or the addition of chemical groups.
  6. Protein folding and targeting: The protein may fold into its native conformation and be targeted to specific cellular compartments.

User Qoheleth
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