Final answer:
The most relevant investigation would focus on whether unusually warm weather is more common globally, which could support the argument that observed local weather patterns are a sign of broader global warming.
Step-by-step explanation:
When evaluating George's argument that global warming is indicated by local weather patterns such as springlike weather during winter and delayed autumn leaf coloration, it would be most relevant to investigate whether unusually warm weather is occurring elsewhere on the globe more frequently than before. This could help ascertain if the observed local weather variations are part of a broader trend of rising temperatures which scientists attribute to an increase in greenhouse gases, primarily carbon dioxide and methane, from human activities such as fossil fuel combustion and deforestation.