Final answer:
Cardiac markers specifically indicative of myocardial infarction are Creatine Kinase MB (CK-MB) and Cardiac Troponin-I, which are released by damaged heart muscle cells. The correct final answer to the question is E (Only C & D).
Step-by-step explanation:
Cardiac markers are essential in diagnosing myocardial infarction (MI), commonly known as a heart attack. When myocardial cells are damaged, certain enzymes are released into the bloodstream. Among these, Creatine Kinase MB (CK-MB) and Cardiac Troponin-I are specific markers that indicate myocardial injury. Additionally, Lactate dehydrogenase (LDH), specifically the LDH1 isoenzyme, also becomes elevated in cases of myocardial infarction, though its levels peak and are maintained later in the timeline following an MI. On the other hand, Alkaline phosphatase (ALP), which is not specific to cardiac tissue, typically does not indicate myocardial infarction when elevated.
Which cardiac markers are elevated during a myocardial infarction should include creatine phosphokinase, specifically the MB isoenzyme (CK-MB), and Cardiac Troponin-I, which are released by damaged cardiac muscle cells. Lactate dehydrogenase, particularly the LDH1 isoenzyme, also is indicative of heart damage. Hence, the correct options are C (Troponin-I) and D (CK-MB), making the final answer E (Only C & D).