Final answer:
Supplements of folate, vitamin B6, and vitamin B12 can help lower homocysteine levels in healthy men with elevated homocysteine. These vitamins are involved in the methylation and interconversion of homocysteine, ultimately converting it to methionine. Lowering homocysteine levels can help prevent conditions like megaloblastic anemia and neurological lesions.
Step-by-step explanation:
When healthy men with elevated homocysteine are given supplements of folate, vitamin B6, and vitamin B12, it can help lower their homocysteine levels.
These vitamins play important roles in homocysteine metabolism. Folate helps convert homocysteine to methionine, while vitamin B6 is involved in the interconversion of glutamic acid and β-methyl aspartic acid. Vitamin B12, on the other hand, is needed for the remethylation of homocysteine to methionine.
By taking these supplements, it helps to lower homocysteine levels, which can be beneficial for preventing conditions associated with high homocysteine levels such as megaloblastic anemia, demyelination, neurological lesions, and infertility.