Final answer:
The Native American Removal Act of 1830 forced the relocation of Native tribes to lands west of the Mississippi River for the purpose of acquiring their lands for White settlement and expansion.
Step-by-step explanation:
The Native American Removal Act of 1830 forced the relocation of Native tribes east of the Mississippi River to lands west of the river. The act was primarily motivated by the desire to acquire Native American lands for White settlement and expansion. It was justified by the belief that Native Americans were obstacles to progress and civilization, and that their removal would secure land for the growing White population. The act resulted in multiple forced removals, including the infamous 'Trail of Tears,' which saw thousands of Native Americans die during the journey to their new lands.