Final answer:
Progressive-relapsing MS is the most aggressive form of multiple sclerosis, often leading to rapid progression and being potentially fatal within a few years. The disease is autoimmune in nature, attacking the myelin sheath and leading to various neurological symptoms. No cure exists, but treatments aim to manage symptoms and slow progression.
Step-by-step explanation:
Progressive-relapsing MS (PRMS) is the type of multiple sclerosis considered to be most aggressive and can be fatal within a few years after diagnosis. Multiple sclerosis (MS) is an autoimmune disease characterized by the destruction of myelin sheath in the central nervous system, leading to impaired nerve signaling and a variety of neurological symptoms.
There are four recognized forms of MS: Relapsing-remitting MS (RRMS), Primary progressive MS (PPMS), Secondary progressive MS (SPMS), and Progressive-relapsing MS (PRMS). PRMS is the least common type of MS and entails both steadily worsening function from the beginning and clear relapses, or attacks, of increased symptoms. Unlike other forms of MS, which may be managed for many years with treatments and lifestyle adjustments, PRMS is known for a more rapid progression that can be challenging to manage and can lead to a decrease in life expectancy.
Unfortunately, there is no known cure for MS, and the treatments available aim to manage symptoms and slow disease progression. In cases of PRMS, aggressive immunomodulatory therapies and symptom management are key strategies used to improve quality of life.