Final answer:
For platelet dysfunction secondary to uremia, treatment usually includes dialysis and medications such as desmopressin, erythropoietin, or conjugated estrogens, and sometimes blood transfusions.
Step-by-step explanation:
Platelet dysfunction secondary to uremia should be treated by correcting the underlying uremic condition, which often involves dialysis to remove waste products and improve platelet function. Additionally, drugs like desmopressin (DDAVP), erythropoietin, or conjugated estrogens may be used to improve platelet function. In some cases, blood transfusions might be necessary to correct significant anemia and improve platelet dysfunction.
While addressing platelet dysfunction, it is important to manage the pre-renal causes that contribute to uremia, which could be characterized by an increase in blood urea up to 300 mg/dl before kidney disorders manifest. Medical professionals need to identify and treat the underlying issues leading to decreased kidney perfusion to prevent further complications.