Final answer:
Pemphigus vulgaris is more commonly seen in people of Middle Eastern and Asian descent and is caused by autoantibodies against desmogleins, leading to skin and mucous membrane blistering.
Step-by-step explanation:
Pemphigus vulgaris is an autoimmune disorder that is characterized by blistering of the skin and mucous membranes. It is more commonly seen in people of Middle Eastern and Asian descent. However, it can affect individuals of any ethnic background. The pathogenesis of pemphigus vulgaris involves the production of autoantibodies against desmogleins, which are proteins critical for cell adhesion in the epidermis.
The loss of adhesion leads to the formation of intraepithelial bullae, which are responsible for the clinical manifestations of the disease. It is important for individuals who present with symptoms of pemphigus vulgaris to seek medical attention, as early diagnosis and treatment can significantly improve prognosis.