Answer:
The Krebs cycle, also known as the citric acid cycle or the tricarboxylic acid (TCA) cycle, is a series of chemical reactions that occur in the mitochondria of cells. These reactions are an important part of the process of cellular respiration, which produces energy for the cell.
The key events of the Krebs cycle include the following:
The conversion of acetyl-CoA to citrate by the enzyme citrate synthase. Acetyl-CoA is derived from the breakdown of glucose and other sugars, and citrate is the first intermediate product of the Krebs cycle.
The conversion of citrate to isocitrate by the enzyme aconitase. Isocitrate is the second intermediate of the Krebs cycle.
The conversion of isocitrate to α-ketoglutarate by the enzyme isocitrate dehydrogenase. α-ketoglutarate is the third intermediate of the Krebs cycle.
The conversion of α-ketoglutarate to succinyl-CoA by the enzyme α-ketoglutarate dehydrogenase. Succinyl-CoA is the fourth intermediate of the Krebs cycle.
The conversion of succinyl-CoA to succinate by the enzyme succinyl-CoA synthetase. Succinate is the fifth intermediate of the Krebs cycle.
The conversion of succinate to fumarate by the enzyme succinate dehydrogenase. Fumarate is the sixth intermediate of the Krebs cycle.
The conversion of fumarate to malate by the enzyme fumarase. Malate is the seventh and final intermediate of the Krebs cycle.
The conversion of malate to oxaloacetate by the enzyme malate dehydrogenase. Oxaloacetate is the starting material for the next round of the Krebs cycle.
As the Krebs cycle progresses, electrons are transferred from the intermediates to NADH and FADH2, which are electron carriers. These carriers then transfer the electrons to the electron transport chain, where they are used to produce ATP, the energy-carrying molecule used by cells. The end products of the Krebs cycle are carbon dioxide and water.
Step-by-step explanation: