Final answer:
A tissue with high metabolism produces lots of carbon dioxide and uses much oxygen, leading to the formation of bicarbonate and a decrease in pH due to increased hydrogen ion concentration.
Step-by-step explanation:
A tissue with high metabolism will be producing a lot of carbon dioxide which forms bicarbonate which lowers pH and using a lot of oxygen. Tissues with high metabolic rates consume more oxygen for cellular respiration, resulting in increased production of carbon dioxide. This carbon dioxide reacts with water in the presence of an enzyme called carbonic anhydrase to form carbonic acid, which disassociates into bicarbonate and hydrogen ions, contributing to the lowering of pH. An abundance of hydrogen ions indicates an acidic environment. The utilization of oxygen and production of carbon dioxide is part of the essential process of energy generation in cells.