Final answer:
The correct statement regarding RBCs in urinary sediment is that RBCs of glomerular origin often appear dysmorphic, indicating potential glomerular disease.
Step-by-step explanation:
The correct statement regarding red blood cells (RBCs) in the urinary sediment is: C. RBCs of glomerular origin often appear dysmorphic. When RBCs originate from the glomerulus, they often get distorted as they pass through the damaged glomerular basement membrane, leading to a dysmorphic appearance under the microscope, which can be an indication of glomerular disease. On the other hand, when RBCs are placed in a hypotonic solution, they swell due to osmotic pressure differences, leading to hemolysis. Conversely, in a hypertonic solution, water will flow out of the RBCs causing them to shrink, not swell.