Final answer:
For an older female to cease reproduction and care for her grand-offspring, the factors of age at menopause and the presence of offspring and grand-offspring are important.
Step-by-step explanation:
For an older female to cease reproduction and instead care for her grand-offspring, two factors must be considered: B and C. B refers to the age at which menopause occurs, while C refers to the continued presence of offspring and grand-offspring that require care. In the case of menopause, it typically occurs between the ages of 45 and 55, with an average age of 52. This is when the ovaries lose their sensitivity to hormones and no longer produce viable eggs. Additionally, the presence of offspring and grand-offspring is necessary for the older female to shift her focus towards caregiving, as it provides a reproductive advantage for the family group.