37.8k views
3 votes
Bone resulting from the use of demineralized human graft materials probably forms by:

a. Endochondral Formation
b. Guided Tissue Regeneration
c. Intramembranous Formation
d. Autogenesis

User Loktar
by
8.3k points

1 Answer

4 votes

Final answer:

Bone resulting from the use of demineralized human graft materials likely forms by Intramembranous Formation, a process where bone develops from connective tissue, rather than from a cartilage model which is involved in Endochondral Ossification.

Step-by-step explanation:

Bone resulting from the use of demineralized human graft materials probably forms by c. Intramembranous Formation. Intramembranous ossification is a process where bone develops directly from sheets of mesenchymal connective tissue, compared to endochondral ossification, which involves bone development from hyaline cartilage. In the context of graft materials, specifically demineralized ones, the process favors an environment that leans towards intramembranous ossification, where osteoblasts produce the bone matrix and begin the ossification process without a prior cartilage template.

Osteoprogenitor cells develop into osteoblasts, which secrete osteoid to form bone tissue. Over time, these osteoblasts become osteocytes when trapped within the matrix they've created. This is counter to endochondral ossification, which is typically involved in the initial formation of long bones and most other bones in the body and utilizes a hyaline cartilage model. Considering demineralized grafts, the absence of minerals like calcium in the initial stages is more accommodative for the intramembranous pathway.

User Aravindh Gopi
by
7.8k points