Final answer:
The main treatment for severe HDN post-natal is the administration of RhoGAM, or Rh immune globulin.
Step-by-step explanation:
Severe HDN, or hemolytic disease of the newborn, is a condition in
which red blood cells in a Rhesus positive fetus are destroyed by antibodies produced by a Rhesus negative mother. The main treatment for severe HDN post-natal is the administration of a drug called RhoGAM, or Rh immune globulin. RhoGAM is given to Rhesus negative mothers during weeks 26-28 of pregnancy and within 72 hours after delivery.
The dug prevents the development of Rh antibodies in the mother's immune system, reducing the risk of HDN in future pregnancies.