Question

Example of how to explain recessive allele pedigree chart (cystic fibrosis)

Answer 1

Cystic fibrosis is an autosomal recessive disorder where two copies of the mutant gene are required to develop the disease. The inheritance pattern can be shown in a pedigree chart. If both parents are carriers, there is a 25% chance of their child having cystic fibrosis.

Step-by-step explanation:

An example of an autosomal recessive disorder is cystic fibrosis (CF). The mutant CFTR gene for cystic fibrosis is a recessive gene located on an autosome. An individual must have two copies of the mutant gene to develop the disease. The inheritance pattern of an autosomal recessive disease such as cystic fibrosis can be shown in a pedigree chart. For example, if both parents are carriers (Ff) of the cystic fibrosis gene, there is a 25% chance that their child will have cystic fibrosis (ff).