Final answer:
Intrinsic plus hand position is caused by the pathophysiology of tightness or contracture of the intrinsic muscles of the hand. The most common disease that can lead to intrinsic plus hand position is called Dupuytren's contracture.
Step-by-step explanation:
Intrinsic plus hand position is caused by the pathophysiology of tightness or contracture of the intrinsic muscles of the hand. These muscles, which are located within the hand, control the fine motor movements of the fingers and thumb. When they become tight or shortened, they can cause the hand to assume an intrinsic plus position, where the metacarpophalangeal joints are flexed while the interphalangeal joints are extended. The most common disease that can lead to intrinsic plus hand position is called Dupuytren's contracture. Dupuytren's contracture is a condition where the fascia, or connective tissue, of the palm, thickens and tightens, causing the fingers to permanently curl into the palm. This can result in an intrinsic plus hand position.