Final answer:
Long-term use of combination HRT has been linked to an elevated risk of breast cancer and cardiovascular disease in some women.
Step-by-step explanation:
Long-term use of combination Hormone Replacement Therapy (HRT) has been linked to an elevated risk of breast cancer and cardiovascular disease in some women.
Studies have shown that women taking estrogen-only HRT have a higher risk of breast cancer. Additionally, the Women's Health Initiative study found that the potential positive effects of HRT on cardiovascular disease were not realized in patients taking estrogen-only HRT.
While HRT can alleviate symptoms of menopause, it is important to consider the potential negative side effects. Regular pelvic and breast exams are recommended for women on HRT.
Long-term use of combination Hormone Replacement Therapy (HRT) has been linked to an elevated risk of several types of cancer and cardiovascular diseases in some women. Among these, the main types of cancer associated with prolonged HRT use include breast cancer, ovarian cancer, and endometrial cancer. Additionally, there is an increased risk of stroke, heart attack, blood clots, and gall bladder disease. Studies, such as those from the Women's Health Initiative, have shed light on these risks, leading to a more cautious approach to HRT, recommending it at the lowest effective dose for the shortest duration necessary, and emphasizing the importance of regular health screenings for women undergoing HRT.