Final answer:
Typhoid fever typically presents with high fever, body aches, headache, nausea, lethargy, and a rose-spotted rash; severe cases may lead to jaundice, pulmonary hemorrhaging, and meningitis.
Step-by-step explanation:
The clinical signs and symptoms of typhoid fever are characterized by a high fever, body aches, headache, nausea, lethargy, and a rash that is sometimes described as rose-spotted. Patients with typhoid fever may also experience chills, vomiting, diarrhea, and muscular pain. Disseminated infections can result in more severe complications such as jaundice, pulmonary hemorrhaging, and meningitis. It is important to note that typhoid fever, caused by specific serotypes of S. enterica, particularly serotype Typhi, is a serious illness with a significant risk of mortality if left untreated.