Final answer:
In CNC programming, the letter 'S' followed by a number sets the spindle speed in rpm.
Step-by-step explanation:
In CNC (Computer Numerical Control) programming, the letter S is used to specify the spindle speed in revolutions per minute (rpm). When a number follows the letter S in a CNC code, it tells the machine at what speed to rotate the spindle. For example, if the code reads S1500, this would set the spindle speed to 1500 rpm.