Final answer:
Primary herpes typically presents with cold sores or fever blisters on or around the lips, mouth, or gums due to HSV-1, while genital herpes, often from HSV-2 infection, produces painful genital blisters. The virus is highly contagious, possibly leading to systemic symptoms initially, with recurrent episodes that usually diminish over time.
Step-by-step explanation:
The classic clinical presentation of primary herpes caused by HSV-1 typically includes the development of cold sores or fever blisters, primarily on or around the lips, mouth, or gums. These lesions often blister, break open, and crust over. HSV-1 can also lead to acute herpetic gingivostomatitis, characterized by ulcers in the mouth. Genital herpes, commonly due to HSV-2, presents with painful blisters or ulcers on the genitals, which can recur. Systemic symptoms like fever and swollen lymph nodes may accompany the initial outbreak. In severe cases, the infection can lead to complications such as blindness, encephalitis, or meningitis.
Herpes is highly contagious and can be transmitted even when asymptomatic, through direct contact. Treatment, if required, may include antiviral medications such as acyclovir, famciclovir, or valacyclovir. While the initial outbreak can be more severe, subsequent outbreaks tend to decrease in frequency and severity over time.