Final answer:
Exit blocks in an implanted pacemaker can be caused by localized ischemia, certain drugs, imbalances in the autonomic nervous system, or disease and pathological conditions.
Step-by-step explanation:
There are several causes of an exit block that may result in failure to capture and undersensing in an implanted pacemaker:
- Localized ischemia: Reduced blood flow to a specific area of the heart can result in an exit block, preventing the pacemaker from effectively capturing the heart's electrical signals.
- Certain drugs: Caffeine, digitalis, and acetylcholine can stimulate abnormal electrical activity in the heart, leading to an exit block.
- An imbalance in the autonomic nervous system: Overstimulation from either the sympathetic or parasympathetic divisions of the autonomic nervous system can interfere with the pacemaker's ability to sense and capture the heart's signals.
- Disease or pathological conditions: Various medical conditions, such as heart disease or other pathologies, can disrupt the normal conduction of electrical impulses in the heart and cause exit blocks in the pacemaker.