Final answer:
Raltegravir (Isentress) is an HIV drug known to cause insomnia and vivid or bizarre dreams, as well as other CNS side effects. It is an integrase inhibitor used to prevent the integration of viral DNA into the host genome, which is crucial for the replication of the virus.
Step-by-step explanation:
The HIV drug which can cause insomnia with vivid or bizarre dreams, and CNS side effects is a medication known as Raltegravir (Isentress). Raltegravir is classified as an integrase inhibitor, working to block the integrase enzyme necessary for the integration of HIV DNA into cellular DNA, an essential step in the production of additional HIV particles. It was approved by the FDA in October 2007 and, like other Anti-HIV drugs, helps inhibit viral replication at various phases of the HIV lifecycle.
A large challenge in HIV treatment is the virus's ability to rapidly mutate and become resistant to medications, which can lead to a requirement of a combination therapy or 'cocktail' approach. This often includes using two reverse transcriptase inhibitors in combination with another type of antiretroviral drug to manage resistance and effectively suppress viral replication. However, it is important to note that while these treatments can slow down the progression of AIDS, there is currently no cure for the disease.
Side effects are a significant consideration in HIV treatment regimens. Apart from insomnia, patients may experience other severe and sometimes irreversible side effects such as depression and prostate enlargement.