Final answer:
Neurogenic arthropathy, or Charcot's joint, occurs due to nerve damage leading to diminished sensation and an increased risk for joint injury. The impaired inflammatory response and healing lead to worsening joint damage over time.
Step-by-step explanation:
Neurogenic arthropathy, commonly known as Charcot's joint, results from nerve damage that decreases sensation and the ability to feel pain or detect changes in temperature. Due to the loss of these protective sensations, individuals are more prone to injuries, leading to repeated joint trauma. The body's normal inflammatory response to these injuries is impaired, meaning the damage accumulates over time without sufficient healing. This condition typically affects weight-bearing joints and can cause significant deformity and disability.
Factors contributing to neurogenic arthropathy include chronic diseases such as diabetes or syphilis, which can both harm the nerves. Treatments focus on preventing further joint damage and managing symptoms but often require close monitoring due to the insensate nature of the affected joints.