Final answer:
Cellulitis with systemic signs is typically treated with antibiotics, and the specific treatment depends on the identified pathogen. For streptococcal infections, penicillin is common, while more severe cases like staphylococcal TSS may require clindamycin, vancomycin, or daptomycin along with supportive care.
Step-by-step explanation:
To treat cellulitis with systemic signs, the approach typically includes using antibiotics and may involve identifying the specific pathogen responsible for the infection. If the cellulitis is caused by streptococcal bacteria, antibiotics such as penicillin are usually prescribed, since these pathogens currently show limited resistance. In severe cases, where infections are caused by staphylococci and diagnosed as toxic shock syndrome (TSS), management includes decontamination, debridement, vasopressor administration, and the use of antibiotics such as clindamycin, vancomycin, or daptomycin. For infections like gas gangrene, immediate treatment involves surgical debridement and administration of antibiotics like penicillin G and clindamycin, potentially coupled with hyperbaric oxygen therapy to exploit the anaerobic nature of the causative bacteria.