Final answer:
DRESS Syndrome involves abnormal lab tests such as increased eosinophil count, atypical lymphocytes, and elevated liver enzymes. Treatment centers on stopping the offending drug and providing supportive care with corticosteroids or other immunosuppressants.
Step-by-step explanation:
DRESS Syndrome, also known as Drug Reaction with Eosinophilia and Systemic Symptoms, is a severe drug-induced hypersensitivity reaction that includes a combination of hematologic, dermatologic, and systemic manifestations. When diagnosing DRESS Syndrome, physicians look for abnormalities in certain laboratory tests. These typically include a marked increase in eosinophil count, which is part of a complete blood count (CBC), but may also include atypical lymphocytes, elevated liver enzymes (AST, ALT), and indications of renal impairment (creatinine).
The primary treatment for DRESS Syndrome involves the immediate cessation of the offending drug. Supportive care is also important, and may include the administration of systemic corticosteroids to mitigate the hypersensitivity reaction. In cases where corticosteroids are contraindicated or not well tolerated, other immunosuppressive agents such as cyclosporine may be considered. Monitoring is continuous, as the syndrome can persist or relapse even weeks after discontinuing the drug.