Final answer:
To work up premature thelarche, a doctor will take a thorough medical history, perform a physical examination, and order laboratory tests. Treatment will depend on the underlying cause, if found, or options such as anti-estrogens or aromatase inhibitors may be considered if no underlying cause is found and the breast tissue is causing psychological distress.
Step-by-step explanation:
Premature thelarche refers to the development of breast tissue in girls under the age of 8 without other signs of puberty. It can be a normal variation, but it is important to evaluate for any underlying causes. To work up premature thelarche, a doctor will typically take a thorough medical history, perform a physical examination, and order laboratory tests.
Some common laboratory tests that may be done include measurement of hormone levels (such as luteinizing hormone, follicle-stimulating hormone, estradiol, and prolactin) and bone age x-ray.
If an underlying cause is found, treatment will be directed towards treating the specific cause. If no underlying cause is found and the breast tissue is causing psychological distress to the child, options such as anti-estrogens or aromatase inhibitors may be considered. However, the treatment approach will depend on each individual case and should be discussed with a healthcare provider.