Final answer:
An H block is a laboratory assay used to study different types of leukemia by measuring the inhibition of leukemia cells. The assay involves collecting blood samples, culturing cells, and treating them with purine analogues.
Step-by-step explanation:
An H block is a specific laboratory assay used in medical research to study different types of leukemia, such as Hairy Cell Leukemia (HCL), T-Cell Leukemia (TCL), and Chronic Lymphocytic Leukemia (CLL).
The H block assay involves collecting blood samples from patients, isolating and freezing the cells, culturing them in specific conditions, and then treating them with purine analogues.
The assay measures the uptake of ATP or the incorporation of {³H}-leucine to determine the concentration required to inhibit 50% of the leukemia cells, known as the IC50 value.