Final answer:
True, drug-induced acute urticaria can have severe systemic impact, as it can potentially lead to anaphylaxis, which is a life-threatening condition characterized by airway obstruction, low blood pressure, and shock.
Step-by-step explanation:
The question asks whether drug-induced acute urticaria can have severe systemic impact, and the answer is true. Urticaria, commonly known as hives, can be caused by various stimuli, including medications. In some cases, it can be part of a type I hypersensitivity reaction which can range from localized symptoms to severe systemic ones such as anaphylaxis. Anaphylactic reactions are rapid, systemic allergic responses that can be life-threatening, primarily due to airway obstruction, significant drop in blood pressure, and shock, thus having a severe systemic impact.
In the context of drug-induced acute urticaria, if the reaction extends beyond the skin causing systemic symptoms like difficulty breathing, swelling of the tongue or throat, a drop in blood pressure, or shock, immediate medical attention is necessary. Such reactions can indeed occur after exposure to certain drugs and are medical emergencies.